Treatment of Uremic Pruritus: A Systematic Review

Topical Treatments for Uremic Pruritus in Hemodialysis Patients: A Systematic Review

Background & Objective: Pruritus is a common disruptive symptom in hemodialysis patients and those with chronic renal failure. Although pharmacological treatments could partially reduce pruritus in hemodialysis patients, the definitive treatment remains challenging in these patients. Several studies have been published in this regard, while no reviews have been focused on these articles. The pr...

Treatment Option for Uremic Pruritus

Recent Advances in Treatment for Uremic Pruritus

This review highlights recent advances in pathophysiology and treatment for uremic pruritus, especially focusing on various interventions. Pruritus in patients on hemodialysis (HD) and peritoneal dialysis (PD) still remains an unresolved issue. Recently, the efficacy and safety of nalfurafine hydrochloride have been reported in Japan, and at present, more than thirty thousand patients receive t...

Efficacy of oral Granisetron in uremic pruritus

Background and aim: Uremic pruritus is a relatively common and distressing problem for patients with chronic renal failure. Serotonin and histamine have been reported as possible mediators of uremic pruritus. Granisetron, a potent and selective inhibitor of 5-HT3 receptors was developed for relief of chemotherapy induced nausea. There are some studies about effect of Ondansetron in uremic...

Gabapentin for uremic pruritus in hemodialysis patients: a qualitative systematic review.

PURPOSE OF THE REVIEW Uremic pruritus (UP) is a common discomfort of dialysis-dependent end-stage renal disease. Some studies suggest a neuropathic cause of UP. Gabapentin, an anticonvulsant, has shown promising results as an emerging drug to treat this condition. OBJECTIVE An updated qualitative systematic review was conducted to evaluate its efficacy and safety in hemodialysis patients. S...